Mucin biology is dynamic and the processes of degradation and turnover are well integrated with biosynthesis to maintain a continuous mucosal protection against all external aggressive forces. Interaction of mucins with microflora plays an important role in normal function.

The project will take place in Mucin Biology Groups, amidst the largest of scientists in the world working on mucins and bacterial interactions

Aberrations in O-glycosylation are responsible for certain human diseases and are associated with disease risk factors. Recent studies have demonstrated essential roles for mucin-type O-glycosylation in protein secretion, stability, processing, and function. 1997-11-01 2006-06-01 A practical guide to developing virtual and augmented reality exercises for teaching structural biology 2020-11-24 The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. pubmed.ncbi.nlm.nih.gov 2020-04-22 Biology Group.

Mucin biology group

28 Jan 2018 From Wikipedia (emphasis mine):. Mucins are a family of high molecular weight, heavily glycosylatedproteins (glycoconjugates) produced by 27 Feb 2021 Mucin in the largest biology dictionary online. Free learning resources for students covering all major areas of biology. We are the Max Planck Institute of Molecular Cell Biology and Genetics (MPI- CBG). We do pioneering basic research. 500 curiosity-driven scientists from over Correlation between mucin biology and tumor heterogeneity in lung cancer. Mucins (MUC) are a family consisting of large O-glycoproteins whose primary Europe PMC is a service of the Europe PMC Funders' Group, in partnership wit The MUCIN BIOLOGY GROUPS are led by Gunnar C. Hansson, Malin E.V. Johansson, Thaher Pelaseyed, and George Birchenough and are among the major http://www.medkem.gu.se/mucinbiology.

Users can perform simple and advanced searches based on annotations relating to sequence, structure and function. These molecules are visualized, downloaded, and analyzed by users who range from students to specialized scientists.

2011-05-03 · May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers.

Mer information. Research Team.

University of Gothenburg | GU · Department of Chemistry & Molecular Biology. Postdoc - Mucin Biology Group.

Aberrant glycosylation occurs in essentially all types of cancers and results in increased sialylation.

Thus, when the mucin MUC1 is expressed on cancer cells, it is decorated by multiple short, sialylated O-linked glycans (MUC1-ST). Brendan Dolan currently works at the Department of Medical Biochemistry and Cell Biology, University of Gothenburg. Brendan is a postdoctoral researcher in the Mucin Biology Group All mucins are highly O-glycosylated by variable glycans depending on species, histoblood group and organ. This makes the intestinal main mucin MUC2 non-degradable by the host digestive system but 2008-02-26 · Mucin-like protein 3. Gene. MUCL3.
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Protein family/group databases. MEROPS i: I08.953: Names National Institutes of Health The European Molecular Biology Laboratory State Secretariat for Education, 2018-08-06 Math Biology Seminar. Mucin Exocytosis.

The mucin O-glycosylation of 10 individuals with and without gastric disease was examined in 1 From the ‡Department of Medical Biochemistry and Cell Biology , Institute of Blood group I antigens, as well as terminal α1,4-GlcNAc-lik Intestinal bacterial populations growing on mucin surfaces were shown to be phylogenetically Bacteria belonging to the Bacteroides fragilis group were isolated and enumerated Methanogens: reevaluation of a unique biological group Molecular Biology and Evolution, Volume 17, Issue 8, August 2000, Pages 1175– 1184, The second group consists of the two large mucins MUC3 and MUC4, The mucin granules fuse with the plasma membrane of the secretory cells and following sified into functional groups including defensive proteins, growth fac-.
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mucin.; Biologi med inriktning mot mikrobiologi; Biology with specialization in Abstract : The diplomonads are a diverse group of eukaryotic microbes found

Mucin gels were rapidly colonized by heterogeneous bacterial populations, especially members of the Bacteroides fragilis group, enterobacteria, and clostridia. Intestinal bacterial populations growing on mucin surfaces were shown to be phylogenetically and metabolically distinct from their planktonic counterparts. Abstract. Mucin-type O-linked glycosylation is a fundamental post-translational modification that is involved in a variety of important biological processes.

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TIM-1 (T-cell immunoglobulin and mucin domain1), also known as KIM-1 (kidney injury molecule 1), is a transmembrane protein expressed on various immune cells and epithelial cells, involved in the modulation of the inflammatory and immune responses. 1 It also acts as a scavenger receptor for oxidized LDL (low-density lipoprotein) and phosphatidylserine, participating in the phagocytosis of

Protein family/group databases.